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pentobarbital will decrease the level or influence of isavuconazonium sulfate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will decrease the level or impact of aripiprazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Even so, based upon the out there info, the window of vulnerability to those variations is considered to correlate with exposures inside the 3rd trimester of gestation from the very first quite a few months of lifetime, but could increase out to roughly 3 yrs of age in human beings (see “Safeguards-Pregnancy and Pediatric Use” and “Animal Pharmacology And/Or Toxicology”).
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pentobarbital will decrease the extent or influence of finasteride by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
pentobarbital will lessen the level or impact of lapatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lessen the level or impact of artemether/lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear here of or Use Alternate Drug. Coadministration with powerful CYP3A4 inducers can result in decreased serum concentrations and lack of antimalarial efficacy
Practitioners should really give the subsequent facts and directions to patients getting barbiturates.
pentobarbital will lower the extent or outcome of felodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will reduce the extent or outcome of nicardipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lower the extent or influence of ethinylestradiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. The efficacy of hormonal contraceptives may be lessened. Utilization of a nonhormonal contraceptive is recommended.